Soho had long been a traditional place for gay people to hang out: Harry's Restaurant in Lisle Street was noted as a "resort of perverts and women of Ill-repute" in the 1930s. The area experienced a quick and large growth of modern gay bars and eateries in the early 1990s, such as The Village, The Yard and The Edge. In 1984 a Conservative MP, Keith Hampson, was charged with an indecent assault on a man arising from an incident in the Gay Theatre (a gay strip venue) at 69 Berwick Street. Hampson was found not guilty  .
The gay scene of Soho is often thought of as attracting a younger more fashion-conscious and mixed crowd than other gay districts, such as Vauxhall. Soho preceded Vauxhall as a popular place for gay people to hang out, but also followed Earls Court, which was popular in the 1970s and 80s with clones, most notably due to the Coleherne pub and Brompton's nightclub.
Soho Masses at one time provided church services for LGBT Roman Catholics.
Sweatbox Soho is a gay sauna and gym.
On 30 April 1999, two people were killed and many injured when the Admiral Duncan pub was blown up using a nail bomb. It was a Friday night and the start of a long bank holiday weekend. Many people had finished work and were enjoying the spring evening in Soho.
Famous people who frequented
Film director Derek Jarman was often seen drinking in Comptons.
- https://en.wikipedia.org/wiki/Soho_walk-up During the mid–2000s several walk-ups on streets leading off Shaftesbury Avenue were bought up and closed or renovated for other uses. By the end of 2014 the gentrification of Soho had reduced the number of flats used for prostitution to around 40, it has since reduced to about a dozen walk-ups
- Matthew Parris and Kevin Maguire Great Parliamentary Scandals, Robson Books, 1995 , p266, 263